of Newton and Woods Hole, MA, on November 6, 2015. Beloved wife of Dr. Kurt J. Isselbacher. Devoted mother of Dr. Kate Isselbacher and her husband, Dr. Alan Epstein, Jody Isselbacher, Dr. Eric Isselbacher and his wife, Dr. Anne Becker, and the late Lisa Isselbacher and her surviving husband Juan Ramirez. Cherished grandmother of Alexandra Epstein, Jennifer Coukas, Brian Isselbacher, Andrew (AJ) Coukos, Adam Isselbacher, and Juliet, Isabel and Henry Isselbacher. Services at The Wilson Chapel, 234 Herrick Rd., Newton Centre, MA, on Sunday, November 8, 2015 at 9:30 am. Interment at Woods Hole Village Cemetery, 22 Church Street, Woods Hole, MA at 2:00 pm. Memorial observance at her residence Monday and Tuesday 6-8 pm. In lieu of flowers remembrances to The Massachusetts General Hospital Cancer Center, 149 13th St., Charlestown, MA 02129.